QRS prolongation is defined as when the conduction of the QRS complex, which represents origination in the SA node, conduction through the Bundle of His, and polarization/repolarization of the ventricles.
Thorough QT/QTc (TQT) Overview Delays in cardiac repolarization can lead to life-threatening heart arrhythmias. As part of a typical drug development program, a sponsor must assess the potential for cardiac repolarization delays following administration of their...
