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QRS Prolongation

QRS prolongation is defined as when the conduction of the QRS complex, which represents origination in the SA node, conduction through the Bundle of His, and polarization/repolarization of the ventricles.


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Thorough QT (TQT)

Thorough QT/QTc (TQT) Overview Delays in cardiac repolarization can lead to life-threatening heart arrhythmias. As part of a typical drug development program, a sponsor must assess the potential for cardiac repolarization delays following administration of their...